Curated work with plain-English summaries so collaborators, clinicians, and students can grasp the impact quickly.
High-resolution CosMx sequencing ties myeloid neighborhoods to H3K27M tumor evolution during GD2-CAR therapy.
Role: Co-led spatial inferences and CAR T response analytics.
Multi-cohort biomarker signature that stratifies outcomes prior to CAR T infusion in lymphoma.
Role: Designed the machine learning stack and prospective validation pipeline.
Connects chemokine-driven macrophage states with post-infusion CAR T failure and charts intervention points.
Role: Led the single-cell integration and interactome modeling.
View ->Joint single-cell, spatial, and serum proteomic monitoring across GD2-CAR therapy.
Role: Architected longitudinal data model and multi-omic harmonization.
Characterizes anti-CAR immune responses that influence durability of GD2-CAR therapy in pediatric brain tumors.
Role: Led computational analysis of antibody repertoires and survival associations.
Weakly supervised learning reveals cell states to target for durable CD19-CAR responses.
Role: Developed the MIL framework and interpretability tooling.
Attention-based MIL links diagnostic single-cell data to clinical outcomes for CAR T therapy.
Role: Driving methodology and benchmarking across multi-site datasets.
Catch-bond receptor engineering strategy that rescues self-antigen recognition for solid tumors.
Role: Contributed translational analytics on engineered T cell persistence.
View ->Cross-indication biomarker atlas forecasting efficacy across hematologic CAR programs.
Role: Built the harmonized feature store and calibration pipelines.
Maps immune niches across glioblastoma and highlights infiltration programs for intervention.
Role: Delivered spatial statistics and visual analytics for the abstract.
View ->Multiomic signatures that anticipate IEC-HLH-like toxicities after CD22-CAR therapy.
Role: Co-developed the multiomic analysis and toxicity classifier.
View ->Quantified esophageal mechanics to differentiate EGJOO phenotypes using high-resolution manometry.
Role: Implemented the biomechanics pipeline and visualization suite.
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